Download Basic Concepts in Biochemistry A Student's Survival Guide by Hiram Gilbert PDF

By Hiram Gilbert

This moment version maintains to innovatively evaluation the hardest recommendations in biochemistry for max comprehension in a quick time period. not like traditional texts or evaluate books that tension memorizing proof, uncomplicated ideas stresses the gaining knowledge of of basic strategies, in order that the reader really comprehends the cloth and feels cozy employing it. Dr. Gilbert makes use of basic, jargon-free language and award-winning instructing strategies together with algorithms, mnemonics and scientific examples.

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The spatial range of the van der Waals attraction depends on the nature of the interacting atoms. For the atoms commonly found in biological molecules, van der Waals attractions are optimal at distances between 3 and 4 Å. 6). van der Waals radius The van der Waals radius is a measure of the size of an atom. The energy due to the van der Waals attraction between two atoms is optimal when they are separated from each other by the sum of their van der Waals radii. If they move closer, the energy increases sharply.

Hydrophilic groups Hydrophilic groups are polar and they can form hydrogen bonds with water. Molecules that are hydrophilic dissolve readily in water. The other amino acids with neutral but polar sidechains are cysteine (Cys, C), serine (Ser, S), threonine (Thr, T), asparagine (Asn, N), glutamine (Gln, Q), histidine (His, H), tyrosine (Tyr, Y), and tryptophan (Trp, W). Although the sidechains of tryptophan and tyrosine contain groups that can form hydrogen bonds with water, other parts of these sidechains are quite hydrophobic.

Guanine contains a carbonyl group (C=O) at position 6 and an amino group at position 2. The oxygen of the carbonyl group is a hydrogen-bond acceptor, and the amino group is a hydrogen-bond donor. 18 Pyrimidine and purine. Four representations of the structures of (A) pyrimidine and (B) purine. 19 Structures of the substituted purines and pyrimidines found in DNA and RNA. 11). The sugars are attached to the nitrogens at the 9 and 1 positions in purine and pyrimidine nucleotides, respectively. The single-letter codes for each base are shown below the full name.

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