Download Casarett & Doull's Essentials of Toxicology (2nd Edition) by Curtis D. Klaassen, John B. Watkins III PDF

By Curtis D. Klaassen, John B. Watkins III

The so much concise and authoritative advent to the foundations of toxicology and the way poisons impact the human physique – now in complete color

Casarett & Doull's necessities of Toxicology is an easy-to-absorb distillation of the field's gold-standard textual content Casarett & Doull's Toxicology: the elemental technology of Poisons. awarded in complete colour for the 1st time, the e-book combines an available and interesting technique with insurance of crucial introductory ideas to supply you with a great grounding in easy and scientific toxicology. Succinct, but accomplished, the textual content covers crucial ideas, toxicokinetics, how poisonous results are handed directly to succeeding generations, how each one physique approach responds to poisons, and the categorical results of a variety of poisonous brokers – from insecticides to radiation.

• a whole simple evaluate of toxins and their scientific management
• displays the services of greater than fifty well known contributors
• A precis of vital issues is incorporated at the start of every bankruptcy and multiple-choice evaluation questions seem on the conclusion
• vital chapters on vanguard subject matters corresponding to Analytic/Forensic Toxicology, medical Toxicology, Occupational Toxicology, pollution, and Ecotoxicology

Condensed desk of Contents: basic rules of Toxicology, Disposition of Toxicants, Nonorgan-Directed Toxicity, objective Organ Toxicity, poisonous brokers, Environmental Toxicology, purposes of Toxicology.

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Extra resources for Casarett & Doull's Essentials of Toxicology (2nd Edition)

Example text

Thus, dose-response characterization of these effects has become an integral and important part of the field of toxicologic pathology. As understanding the biology of disease at the molecular level that is caused by poisons is necessary to be able to predict low-dose extrapolations of disease, a considerable amount of research has gone into developing appropriate models that will predict these adverse effects. The toxicologic pathologist must have a mastery of both experimental and comparative pathology.

Introduction II. Genomics: High-Density Nucleic Acid Microarrays III. Proteomics IV. Metabonomics: Pattern Recognition Nuclear Magnetic Resonance Spectroscopy V. Laser Capture Microscopy VI. Computational Modeling VII. Summary Chapter 12: Issues in Laboratory Animal Science for the Toxicologic Pathologist I. Introduction II. Regulatory Issues III. Selection of Animal Models IV. Animal Health Considerations V. Housing and Husbandry Issues VI. The Role of Diet in Toxicology Studies VII. Summary Chapter 13: New Animal Models in Toxicology I.

Groton, Connecticut 06340 Hugh E. Black(1:419), Hugh E. , Sparta, New Jersey 07871 Patricia M. Blakley(2:895), Kinsmen Children’s Centre and Department of Pediatrics, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W8 Brad Bolon(2:509), Amgen, Thousands Oaks, California 91320 Ronald W. , Guelph, Ontario, Canada N1H 7K9 Karrie A. Brenneman(2:509), IDDEX, Portland, Oregon Thomas J. E. , Global Research and Development, Groton, Connecticut 06348 Charles C. Capen(2:681), Department of Veterinary Biosciences, The Ohio State University, Columbus, Ohio 43210 Bruce D.

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