Download Drug Metabolism Concepts by Donald M. Jerina (Eds.) PDF

By Donald M. Jerina (Eds.)

content material: Cytochrome P-450 : its position in oxygen activation for drug metabolism / R.W. Estabrook and J. Werringloer --
man made types for the response phases of cytochrome P-450 / James P. Collman and Thomas N. Sorrell --
Biochemical reviews on drug metabolism : isolation of a number of different types of liver microsomal cytochrome P-450 / M.J. Coon, J.L. Vermilion, K.P. Vatsis, J.S. French, W.L. Dean, and D.A. Haugen --
solution of a number of types of rabbit liver cytochrome P-450 / Eric F. Johnson and Ursula Muller-Eberhard --
Enantiomeric selectivity and perturbation of product ratios as equipment for learning the multiplicity of microsomal enzymes / William F. Trager --
position of purified cytochrome P-448 and epoxide hydrase within the activation and cleansing of benzo[a]pyrene / W. Levin, A.W. wooden, A.Y.H. Lu, D. Ryan, S. West, A.H. Conney, D.R. Thakker, H. Yagi, and D.M. Jerina --
In vitro reactions of the diastereomeric 9,10-epoxides of (+) and ( --
)-trans-7,8-dihydroxy-7,8-dihydrobenzo-[a]pyrene with polyguanylic acid and facts for formation of an enantiomer of every diastereomeric 9,10-epoxide from benzo[a]pyrene in mouse pores and skin / P.D. Moore, M. Koreeda, P.G. Wislocki, W. Levin, A.H. Conney, H. Yagi, and D.M. Jerina --
function of metabolic activation in chemical-induced tissue harm / Sidney D. Nelson, Michael R. Boyd, and Jerry R. Mitchell.

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J. , J. Biol. Chem. (1957) 225, 103114. 32. , and Rosenthal, O. in 24 33. 34. 35. 36. ch001 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. DRUG M E T A B O L I S M CONCEPTS "Biological and Chemical Aspects o f Oxygenases" e d i t e d by K. Bloch and O. H a y a i s h i , pgs. 153-170, Maruzen Co. , Tokyo (1966). , Schenkman, J. , Molec. Pharmacol. (1966) 2, 187-190. , Molec. Pharmacol. (1967) 3, 113-123. , Biochem. Biophys. Res. Comm. (1968) 23, 264-268. , Peterson, J. and Ishimura, Y.

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I . , J. Biol. Chem. (1971) 246, 4143-4150. 9. , Proc. Nat'l. (USA) (1974) 71, 4565-4569. 10. , Biochemistry (1971) 10, 1556-1560. 11. , J. Biochem. (Tokyo) (1971) 69, 155-168. 12. W. and Fridovich, I . , J. Biol. Chem. (1975) 250, 8812-8817. 13. S. , Annals o f Clinical Research (1976), Vol. 8, s u p p l . 17, 18-27. 14. M. , A r c h i v e s Biochem. Biophys. (1972) 150, 116-125. 15. F. , A r c h i v e s Biochem. Biophys. (1974) 162, 83-92. 16. , HoppeS e y l e r ' s Z. Physiol. Chem. (1976) 357, 1067.

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