By Hans Schreier
Demonstrates how substitution of numerous ligands can render albumin a flexible concentrating on device for selective drug accumulation in a number of mobilephone populations of the liver! Considers the efforts in biotechnology and molecular biology to supply clever drug supply units via exploiting organic pathways! Containing over 1100 references to facilitate additional examine, Drug concentrating on expertise updates fresh development in oral and colonic concentrating on expertise utilizing pH- and enzyme-sensitive coating fabrics and novel polymer platforms. Suggesting harnessing organic approaches because the final method of the supply or expression of pharmacologically lively brokers, Drug focusing on expertise is a top-shelf reference for pharmacists, pharmacologists, and pharmaceutical scientists analytical, floor, actual, and colloid chemists and biochemists and upper-level undergraduate and graduate scholars in those disciplines.
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Extra resources for Drug Targeting Technology: Physical, Chemical, Biological Methods
O. M. Wrong, A. J. Vince, and J. C. Waterlow, The contribution of endogenous urea to faecal ammonia in man, determined by 15N labelling of plasma urea, Clin. Sci. 68:193–199 (1985). 38. G. L. Simon, and S. L. Gorbach, The human intestinal microflora, Digest. Dis. Sci. ):147S–162S (1986). 39. R. Prizont, N. Konigsberg, Identification of bacterial glycosidases in rat cecal contents, Digest. Dis. Sci. 26:733–777 (1981). 40. D. Wong, S. Larrabee, K. Clifford, J. Tremblay, and D.
Gorbach, The human intestinal microflora, Digest. Dis. Sci. ):147S–162S (1986). 39. R. Prizont, N. Konigsberg, Identification of bacterial glycosidases in rat cecal contents, Digest. Dis. Sci. 26:733–777 (1981). 40. D. Wong, S. Larrabee, K. Clifford, J. Tremblay, and D.
17. S. S. Rao, and W. A. Ritschel, Development and in vitro/in vivo evaluation of a colonic release capsule of vasopressin, Int. J. Pharmaceut. 86:35–41 (1992). 18. S. S. Rao, and W. A. P. Pharma Sciences 5:19–29 (1995). 19. A. Rubinstein, B. Tirosh, M. Baluom, T. Nassar, A. David, R. Radai, I. Gliko-Kabir, and M. Friedman, The rationale for peptide drug delivery to the colon and the potential of polymeric carriers as effective tools, J. Controlled Release 46:59–73 (1996). 20. N. Gardner, W. Haresign, R.
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